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pharmacology unit one Flashcard

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pharmacology

pharmacology
the study of effects of chemical substances, their sources, nature, and properties and the study of the body's reaction to the drugs
the study of effects of chemical substances, their sources, nature, and properties and the study of the body
drug
any chemical substance that, when administered, produces a change in function
any  chemical substance that, when administered, produces a change in function
ethnopharmacology
study of ethnic groups and use of drugs
study of ethnic groups and use of drugs
Kefauver-Harris Amendment (1962)
makes sure a drug actually works
makes sure a drug actually works
duration of action
how long the drug lasts in the body
how long the drug lasts in the body
chemical name
describes the drugs chemical structure
describes the drugs chemical structure
controlled substances act (1970)
regulates possession and use of certain products
regulates possession and use of certain products
antagonists
drugs that prevent receptor activation and block a response
drugs that prevent receptor activation and block a response
loading dosage
dose of drug given to achieve a rapid minimum concentration
dose of drug given to achieve a rapid minimum concentration
pharmacodynamic phase
the study of the drug concentration and its effects on the body
the study of the drug concentration and its effects on the body
peak action
when drug is highest in the blood stream
when drug is highest in the blood stream
absorption
passive diffusion, facilitated diffusion, active absorption, and pinocytosis (cell drinking)
passive diffusion, facilitated diffusion, active absorption, and pinocytosis (cell drinking)
distrubtion
movement of drug from circulation to the body tissue
movement of drug from circulation to the body tissue
Durham-Humphrey Amendment (1952)
defined 2 categories for meds: over the counter and prescription
defined 2 categories for meds: over the counter and prescription
HIPPA
patient privacy act
patient privacy act
Pharmacokinetic process
A: Absorption
D: distrubtion
M: Metabolism
E: excretion
A: Absorption <br />D: distrubtion <br />M: Metabolism <br />E: excretion
additive effect
when 2 drugs are administered in combination and the response is increased beyond what either drug could produce alone
when 2 drugs are administered in combination and the response is increased beyond what either drug could produce alone
pure food and drug act (1906)
prevents sale of misbranded or poisonous food, drugs, and medicine
prevents sale of misbranded or poisonous food, drugs, and medicine
agonist
drugs that activate receptors and produce a desired response
drugs that activate receptors and produce a desired response
metabloism
process by which the body chemically changes drugs into a form that can be excreted
process by which the body chemically changes drugs into a form that can be excreted
contraindicatation
medical situations when the drug should not be administered
medical situations when the drug should not be administered
synergistic effect
mixing 2 drugs together to increase affect of other drugs
mixing 2 drugs together to increase affect of other drugs
adverse drug reactions
unintentional, unexpected, reactions to drug that occur at normal drug dosage; bad
unintentional, unexpected, reactions to drug that occur at normal drug dosage; bad
hepatic first-pass effect
drugs taken PO are routed to the liver first to be metabolized and it may reduce the amount of bioavailability
drugs taken PO are routed to the liver first to be metabolized and it may reduce the amount of bioavailability
absorption
movement of the drug into the blood stream after administration
movement of the drug into the blood stream after administration
Food and drug administration act (1997)
modernized the FDA
modernized the FDA
bioavalability
percentage of administered drug available for activity
percentage of administered drug available for activity
side effects
physiologic effects not related to desired drug effects; may be good or bad
physiologic effects not related to desired drug effects; may be good or bad
pharmaceutic phase
first phase of drug action: disintegration and dissolution
first phase of drug action: disintegration and dissolution
clinical pharmacolgy
the study of drugs used to treat, diagnose, or prevent a disease
the study of drugs used to treat, diagnose, or prevent a disease
tachyphylaxis
acute, rapid decrease in drug responsiveness regardless of time
acute, rapid decrease in drug responsiveness regardless of time
Harrison Narcotic Act
Taxed drugs
Taxed drugs
pharmacogentecis
study of genetic factors influencing individual response
study of genetic factors influencing individual response
drug interactions
altered or modified action or effects of a drug result due to interaction with one or more drugs
altered or modified action or effects of a drug result due to interaction with one or more drugs
nonspecific
drugs that affect multiple receptor sites
drugs that affect multiple receptor sites
nonselective
drugs that affect multiple receptors
drugs that affect multiple receptors
onset
when drug first starts working
when drug first starts working
united states pharmacopeia
makes drug standards for the U.S.
makes drug standards for the U.S.
excretion
drugs must be unbound, water soluble, influenced by Ph, influenced by kidney function
drugs must be unbound, water soluble, influenced by Ph, influenced by kidney function
tolerance
decreased drug responsiveness over time
decreased drug responsiveness over time
placebo effect
drug response not attributed to chemical properties
drug response not attributed to chemical properties
Sherley Amendment (1912)
prohibited false and fraudulent labeling of drugs
prohibited false and fraudulent labeling of drugs
ethnomedicine
study of ways people in different cultures conceptualize health and illness
study of ways people in different cultures conceptualize health and illness
culturally sensitive
alert to pts cultural expectations
alert to pts cultural expectations
brand (trade name)
chosen by the drug company and is usually a registered trademark
chosen by the drug company and is usually a registered trademark
toxic effects
identified by monitoring the plasma therapeutic range of the drug; really bad
identified by monitoring the plasma therapeutic range of the drug; really bad
Food, Drug, and Cosmetic act (1938)
oversee safety of food, drugs, and medical devices
oversee safety of food, drugs, and medical devices
off-label use
a med used for something it has not been approved for but it still works for the diagnosis
a med used for something it has not been approved for but it still works for the diagnosis
controlled substances
abuse potential
abuse potential
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Cassidy Kennedy
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